New 'Genetic Bar Code' Technique Establishes Ability to Derive DNA Information from RNA

ScienceDaily (Apr. 8, 2012) — Researchers from Mount Sinai School of Medicine have developed a method to derive enough DNA information from non-DNA sources -- such as RNA -- to clearly identify individuals whose biological data are stored in massive research repositories. The approach may raise questions regarding the ability to protect individual identity when high-dimensional data are collected for research purposes.

A paper introducing the technique appears in the April 8 online edition of Nature Genetics.

DNA contains the genetic instructions used in the development and functioning of every living cell. RNA acts as a messenger that relays genetic information in the cell so that the great majority of processes needed for tissue to function properly can be carried out.

To date, access to databases with DNA information has been restricted and protected as it has long been considered the sole genetic fingerprint for every individual. However, vast amounts of RNA data have been made publicly available via a number of databases in the United States and Europe. These databases contain thousands of genomic studies from around the world. Read More